Синтез 2-гидрокси-5(3-метилциклогексил) ацето- и бензофенонов в присутствии нано-каталитической системы
Haydarli G.Z., Rasulov Ch.K., Alieva N.M.
(Institute of Petrochemical Processes of the Ministry of Science and Education of Azerbaijan)
Keywords: phenol, 3-methylcyclohexene, cycloalkylation, p-(3-methylcyclohexyl) phenol, acetic acid, benzoyl chloride, catalyst, acylation, acetophenone, benzophenone
Abstract. The results of studying of the cycloalkylation reaction of phenol with 3-methylcyclohexene in the presence of zeolite Y impregnated with phosphoric acid are presented. It was found that in order to achieve a high yield (71.2%) and selectivity (93.7%) during the cycloalkylation reaction of phenol with 3-methylcyclohexene, the reaction conditions should be as follows: reaction temperature 120 oC, molar ratio of phenol to 3-methylcyclohexene 1:1, volume velocity 0.5 h-1. The results of the synthesis of 2-hydroxy-5(3-methylcyclohexyl) aceto- and benzophenones by the reaction of p-(3-methylcyclohexyl) phenol with acetic acid (AcOH) and benzoyl chloride (BzCl) with the participation of nanosized ZnCl2 as a catalyst are presented. It was found that at a temperature of 140 oC, a reaction time of 40 minutes, and a molar ratio of p-(3-methylcyclohexyl) phenol to AcOH (BzCl) of 1:2, the yield of the target products was 63.3-66.7%.